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Dec 30, 2024
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CH 243B Organic Chemistry Lab 3 Lab Hours: 3 Credits: 1
Offers a laboratory course to accompany CH 243 Organic Chemistry 3 for students majoring in the physical and life sciences. Emphasizes microscale laboratory synthesis, spectroscopy, biological activity of organic compounds, and qualitative analysis of unknowns. Students requiring lecture and lab credit for transfer must take CH 243 and CH 243B.
Prerequisite: Placement into WR 115 , or completion of WR 090 (or higher); and completion of CH 242B ; or consent of instructor. (All prerequisite courses must be completed with a grade of C or better.) Student Learning Outcomes:
- Describe the structure, properties, nomenclature, synthesis and reactions of carboxylic acids, carboxylic acid derivatives and amines.
- Recognize the relationship between the structure of organic compounds and their subsequent physical and chemical properties.
- Organize and maintain a laboratory notebook and prepare for experimentation in the microscale organic laboratory.
- Translate the principles of organic chemistry into practical use in the organic laboratory.
- Apply organic principles to the study of biological molecules: carbohydrates, lipids, amino acids, proteins and nucleic acids.
- Recognize the organic chemistry basis of biologically important compounds and their reactions.
- Assess the structures of biological molecules and their function in living systems.
Content Outline
- Check-In
- Safety; check-in
- The laboratory notebook
- Disposal of chemical wastes
- Analgesics
- History of aspirin
- Synthesis of aspirin
- Antibacterial agents
- History of immunology and chemotherapy
- Sulfanilamide from nitrobenzene
- Barbiturates and Hypnotic Drugs
- History of barbiturates
- Malonic ester synthesis
- Photochemistry
- Theory of photochemical reactions
- Synthesis of benzopinacol
- Synthesis of luminol
- Sugars
- Carbohydrates and artificial sweeteners
- Mutarotation of sucrose: a rate study
- Analysis of unknowns
- Vitamins
- Background on vitamins
- Quinones
- Synthesis of vitamin K1 - a quinone
- Amino Acids
- Structure and properties
- Enzymatic resolution of DL-alanine
- Lipids
- Structure and properties
- Epoxidation of cholesterol
- Oleic acid from olive oil
- Searching the Chemical Literature
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